This study, titled RESOLVE-D, aims to test the effectiveness of graded sensorimotor retraining for people with chronic low back pain compared to standard care.
The need
Low back pain is the leading cause of disability worldwide and affects nearly four million Australians, with prevalence and costs expected to rise sharply over the next decade. Approximately one in three people with low back pain continue to experience symptoms after three months. Current treatments typically provide only small, short-term benefits. Advances in understanding how chronic pain develops have led to new treatment approaches, including graded sensorimotor retraining, which has shown clinically meaningful and lasting improvements in pain and function in a single centre, sham- controlled, randomised control trial. These promising results will now be further investigated in real-world primary care settings.
About
This trial will investigate the effectiveness and implementation of graded sensorimotor retraining compared to standard care options for chronic low back pain in primary care physiotherapy practice. Comparing graded sensorimotor retraining against real world comparators in real world settings is the next step in the translational pipeline of this intervention.
Impact
- This research will accelerate the translation of a promising treatment model into everyday clinical practice.
- Collaboration with education partners will ensure the findings are directly implemented to benefit people affected by chronic low back pain.
Project Leads
Professor James McAuley
Senior Research Scientist and Group Leader, NeuRA Director, Centre for Pain IMPACT Professor, Faculty of Medicine and Health, UNSW Sydney Honorary Research Fellow, The George Institute for Global Health
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Dr Aidan Cashin
NHMRC Emerging Leadership Fellow Deputy Director, Centre for Pain IMPACT, NeuRA Conjoint Senior Lecturer, Faculty of Medicine & Health, UNSW Sydney Accredited Exercise Physiologist, ESSA
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Project Team
Dr Mathew Bagg
UNDA, NeuRA
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Professor Manuela Ferreira
Program Head, Musculoskeletal Health, The George Institute for Global Health
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Dr Abigail Haynes
Research Fellow, Qualitative Community of Practice Lead, Institute for Musculoskeletal Health
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Dr Hayley Leake
Postdoctoral Research Fellow Honorary Research Fellow at NeuRA Research Fellow at University of South Australia
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Associate Professor Gustavo Machado
Principal Research Fellow, Faculty of Medicine and Health, NHMRC
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Professor Chris Maher
Director of the Institute for Musculoskeletal Health, Professor in the School of Public Health, University of Sydney.
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Professor James McAuley
Medicine &Health, School of Health Sciences, UNSW
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Mr Keith McNaughton
Research Assistant, NeuRA
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Professor Lorimer Moseley
Bradley Distinguished Professor, School of Allied Health and Human Performance, College of Health. Adelaide University
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Dr Saurab Sharma
Medicine & Health, School of Health Sciences, UNSW
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Associate Professor Tasha Stanton
Associate Professor of Clinical Pain Neuroscience, College of Health School of Allied Health and Human Performance, Adelaide University
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Associate Professor Adrian Traeger
Senior Research Fellow, Sydney University Robinson Fellow
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Ms Martjie Venter
PhD Candidate, University of New South Wales
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Professor Benedict Wand
Professor in Physiotherapy, University of Notre Dame Australia
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Professor Chris Williams
Honorary Associate Professor, School of Medicine and Public Health. The University fo Newcastle Australia
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Associate Professor Serene Yoong
Co-Director of the Deakin Centre for Global Preventive Health and Nutrition (GLOBE), Associate Professor, Implementation Science and Health Services, School of Health and Social Development, Faculty of Health
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Funding
Our funding is from a Medical Research Future Funding (MRFF) project grant (RESOLVE-D, MRFF ID: MRF2031758)